2003-2007,中国科技大学高分子科学与工程系,高分子工程学士
2007-2013,中国科技大学高分子科学与工程系,高分子科学博士
博士学位论文:智能响应性聚磷酸酯纳米凝胶用于药物选择性传输的研究
毕业后去向:University of Illinois at Urbana-Champaign
现联系方式: huabear@mail.ustc.edu.cn
所获奖励:Poster Award in 9th World Biomaterials Congress (2012年)、研究生国家奖学金(2012年)、中国科学技术大学优秀博士毕业生(2012年)、“通用电气基金会科技创新奖”二等奖(2012年)、中国科学院朱李月华优秀博士生奖学金(2012年)、中国科学院院长特别奖(2013年)、第八届“中国青少年科技创新奖”(2013年)
研究生期间发表论著:
1. Meng-Hua Xiong, Yan Bao, Xiao-Jiao Du, Hong-Xia Wang, Jun Wang*, Differential Anti-Cancer Drug Delivery with A Nanogel Sensitive to Bacteria-Accumulated Tumor Artificial Environment, ACS Nano, 2013, 7, 10636-10645 (most read articles, ACS Nano, Dec., 2013)
2. Meng-Hua Xiong, Ya-Juan Li, Yan Bao, Xian-Zhu Yang, Bing Hu*, Jun Wang*, Bacteria-Responsive Multifunctional Nanogel for Targeted Antibiotic Delivery, Advanced Materials, 2012, 24, 6175-6180
3. Meng-Hua Xiong, Yan Bao, Xian-Zhu Yang, Yu-Cai Wang, Baolin Sun*, Jun Wang*, Lipase-Sensitive Polymeric Triple-Layered Nanogel for “On-Demand” Drug Delivery, Journal of the American Chemical Society, 2012, 134, 4355-4362 (ESI Highly Cited Papers)
4. Meng-Hua Xiong, Juan Wu, Yu-Cai Wang, Lai-Sheng Li, Xiao-Bing Liu, Guang-Zhao Zhang, Li-Feng Yan, Jun Wang*, Synthesis of PEG-Armed and Polyphosphoester Core-Cross-Linked Nanogel by One-Step Ring-Opening Polymerization, Macromolecules, 2009, 42, 893-896
5. Meng-Hua Xiong, Ling-Yan Tang, Jun Wang*, Synthesis and Properties of Diblock Copolymers of PEG and Poly(2-methoxyethyl ethylene phosphate) for Enhanced Paclitaxel Solubility. Acta Polymerica Sinica, 2011, 8, 853-860
6. Cheng-Qiong Mao, Meng-Hua Xiong, Yang Liu, Song Shen, Xiao-Jiao Du, Xian-Zhu Yang, Pei-Zhuo Zhang, Jun Wang*, Synthetic Lethal Therapy for KRAS Mutant Non-Small-Cell Lung Carcinoma with Nanoparticle-Mediated CDK4 siRNA Delivery, Molecular Therapy, accepted
7. Hong-Xia Wang, Meng-Hua Xiong (co-first author), Jing Zhu, Yu-Cai Wang, Jun Wang*. N-Acetylgalactosamine Functionalized Mixed Micellar Nanoparticles for Targeted Delivery of siRNA to Liver. Journal of Controlled Release, 2013, 166, 106-114
8. Juan Wu, Tian-Meng Sun, Xian-Zhu Yang*, Jing Zhu, Xiao-Jiao Du, Yan-Dan Yao, Meng-Hua Xiong, Hong-Xia Wang, Yu-Cai Wang, Jun Wang*, Enhanced Drug Delivery to Hepatocellular Carcinoma with a Galactosylated Core-Shell Polyphosphoester Nanogel, Biomaterial Sciences, 2013, 1, 1143-1150 (Top 10 Most-accessed Biomaterials Science articles-Q3 2013)
9. Chao Yu, Bing He, Meng-Hua Xiong, Hua Zhang, Lan Yuan, Ling Ma, Wen-Bing Dai, Jun Wang, Xing-Lin Wang, Xue-Qing Wang, Qiang Zhang*, The effect of hydrophilic and hydrophobic structure of amphiphilic polymeric micelles on their transport in epithelial MDCK cells,Biomaterials, 2013, 34, 6284-6298
10. Xi-Qiu Liu, Meng-Hua Xiong, Xiao-Ting Shu, Rui-Zhi Tang, Jun Wang*, Therapeutic Delivery of siRNA Silencing HIF-1 Alpha with Micellar Nanoparticles Inhibits Hypoxic Tumor Growth, Molecular Pharmaceutics, 2012, 9, 2863-2874 (Most read articles, top 10)
11. Xian-Zhu Yang, Shuang Dou, Yu-Cai Wang, Hong-Yan Long, Meng-Hua Xiong, Cheng-Qiong Mao, Yan-Dan Yao, Jun Wang*, Single-Step Assembly of Cationic Lipid-Polymer Hybrid Nanoparticles for Systemic Delivery of siRNA, ACS Nano, 2012, 6, 4955-4965
12. You-Yong Yuan, Wen-Jing Song, Feng Wang, Jin-Zhi Du, Meng-Hua Xiong, Jun Wang*, Biocompatible and Functionalizable Polyphosphate Nanogels with A Branched Structure, Journal of Materials Chemistry, 2012, 22, 9322-9329
13. Feng Wang, Yu-Cai Wang, Shuang Dou, Meng-Hua Xiong, Tian-Meng Sun, Jun Wang*, Doxorubicin-Tethered Responsive Gold Nanoparticles Facilitate Intracellular Drug Delivery for Overcoming Multidrug Resistance in Cancer Cells, ACS Nano, 2011, 5, 3679-3692 (most read article, Q2, 2011)
14. Yu-Cai Wang, Yang Li, Tian-Meng Sun, Meng-Hua Xiong, Juan Wu, Yi-Yan Yang, Jun Wang*, Core-Shell-Corona Micelle Stabilized by Reversible Cross-Linkage for Intracellular Drug Delivery, Macromolecular Rapid Communications, 2010, 31, 1201-1206
15. Yu-Cai Wang, Xi-Qiu Liu, Tian-Meng Sun, Meng-Hua Xiong, Jun Wang*, Functionalized Micelles from Polyphosphoester and Poly(e-caprolactone) Block Copolymer for Receptor-Mediated Drug Delivery, Journal of Controlled Release, 2008, 128, 32-40 (Top 25 Hottest Article)
16. Yu-Cai Wang, Ling-Yan Tang, Tian-Meng Sun, Chang-Hua Li, Meng-Hua Xiong, Jun Wang*, Self-assembled Micelles of Biodegradable Triblock Copolymers Based on Poly(ethyl ethylene phosphate) and Poly(epsilon-caprolactone) as Drug Carriers,Biomacromolecules, 2008, 9, 388-395
17.王均、熊梦华、吴卷,一种生物相容性纳米颗粒及其作为药物输送载体的应用,中国发明专利,授权号:ZL 2010 1 0001808.3