2001-2005,中国科学技术大学化学与材料科学学院,高分子化学学士
2005-2010,中国科学技术大学化学与材料科学学院,高分子科学博士
博士学位论文:聚磷酸酯的控制合成及其在药物传递中的应用
毕业后去向:美国佐治亚理工学院,博士后
现联系方式:qingbo62@mail.ustc.edu.cn
所获奖励:中国科学院“院长奖”(2010年)、中国科学院朱李月华优秀博士生奖(2009年)、获International Conference on Materials for Advanced Technologies 2009最佳墙报奖(2009年)、东港奖学金(2007年)
研究生期间发表论著:
1. Tian-Meng Sun, Yu-Cai Wang (co-first author), Feng Wang, Jin-Zhi Du, Cheng-Qiong Mao, Chun-Yang Sun, Rui-Zhi Tang, Yang Liu, Jing Zhu, Yan-Hua Zhu, Xian-Zhu Yang, Jun Wang*, Cancer Stem Cell Therapy Using Doxorubicin Conjugated to Gold Nanoparticles via Hydrazone Bonds, Biomaterials, 2014, 35, 836-845
2. Juan Wu, Tian-Meng Sun, Xian-Zhu Yang*, Jing Zhu, Xiao-Jiao Du, Yan-Dan Yao, Meng-Hua Xiong, Hong-Xia Wang, Yu-Cai Wang, Jun Wang*, Enhanced Drug Delivery to Hepatocellular Carcinoma with a Galactosylated Core-Shell Polyphosphoester Nanogel, Biomaterial Sciences, 2013, 1, 1143-1150 (Top 10 Most-accessed Biomaterials Science articles-Q3 2013)
3. Wen-Qing Li, Chun-Yang Sun, Feng Wang, Yu-Cai Wang, Yi-Wen Zhai, Meng Liang, Wen-Jing Liu, Zhi-Min Liu, Jun Wang*, Fei Sun*, Achieving a New Controllable Male Contraception by Photothermal Effect of Gold Nanorods, Nano Letters, 2013, 13, 2477-2484
4. Wen-Qing Li, Feng Wang, Zhi-Min Liu, Yu-Cai Wang, Jun Wang*, Fei Sun*, Gold Nanoparticles Elevate Plasma Testosterone Levels in Male Mice without Affecting Fertility, Small, 2013, 9, 1708-1714
5. Hong-Xia Wang, Meng-Hua Xiong, Yu-Cai Wang, Jing Zhu, Jun Wang*, N-Acetylgalactosamine Functionalized Mixed Micellar Nanoparticles for Targeted Delivery of siRNA to Liver, Journal of Controlled Release, 2013, 166, 106-114
6. Xian-Zhu Yang, Shuang Dou, Yu-Cai Wang, Hong-Yan Long, Meng-Hua Xiong, Cheng-Qiong Mao, Yan-Dan Yao, Jun Wang*, Single-Step Assembly of Cationic Lipid-Polymer Hybrid Nanoparticles for Systemic Delivery of siRNA, ACS Nano, 2012, 6, 4955-4965
7. Meng-Hua Xiong, Yan Bao, Xian-Zhu Yang, Yu-Cai Wang, Baolin Sun*, Jun Wang*, Lipase-Sensitive Polymeric Triple-Layered Nanogel for “On-Demand” Drug Delivery, Journal of the American Chemical Society, 2012, 134, 4355-4362
8. Yu-Cai Wang, Feng Wang, Tian-Meng Sun, Jun Wang*, Redox-Responsive Nanoparticles from the Single Disulfide Bond-Bridged Block Copolymer as Drug Carriers for Overcoming Multi-Drug Resistance in Cancer Cells, Bioconjugate Chemistry, 2011, 22, 1939-1945
9. Pim-on Rujitanaroj, Yu-Cai Wang, Jun Wang, Chew Sing Yian*, Nanofiber-Mediated Controlled Release of siRNA Complexes for Long Term Gene-Silencing Applications, Biomaterials, 2011, 32, 5915-5923
10. Feng Wang, Yu-Cai Wang (co-first author), Shuang Dou, Meng-Hua Xiong, Tian-Meng Sun, Jun Wang*, Doxorubicin-Tethered Responsive Gold Nanoparticles Facilitate Intracellular Drug Delivery for Overcoming Multidrug Resistance in Cancer Cells, ACS Nano, 2011, 5, 3679-3692 (most read article, Q2, 2011)
11. Yu-Cai Wang, You-Yong Yuan, Feng Wang, Jun Wang*, Syntheses and Characterization of Block Copolymers of Poly(aliphatic ester) with Clickable Polyphosphoester, Journal of Polymer Science Part A: Polymer Chemistry, 2011, 49, 487-494
12. Yu-Cai Wang, Juan Wu, Yang Li, Jin-Zhi Du, You-Yong Yuan, Jun Wang*, Engineering Nanoscopic Hydrogels via Photo-Crosslinking Salt-Induced Polymer Assembly for Targeted Drug Delivery, Chemical Communications, 2010, 46, 3520-3522
13. Yu-Cai Wang, Yang Li, Tian-Meng Sun, Meng-Hua Xiong, Juan Wu, Yi-Yan Yang, Jun Wang* , Core-Shell-Corona Micelle Stabilized by Reversible Cross-Linkage for Intracellular Drug Delivery , Macromolecular Rapid Communications, 2010, 31, 1201-1206
14. You-Yong Yuan, Qing Du, Yu-Cai Wang, Jun Wang*, One-Pot Syntheses of Amphiphilic Centipede-Like Brush Copolymers via Combination of Ring-Opening Polymerization and “Click” Chemistry , Macromolecules, 2010, 43, 1739-1746
15. Yu-Cai Wang, You-Yong Yuan , Jin-Zhi Du, Xian-Zhu Yang, Jun Wang* , Recent Progress in Polyphosphoesters: From Controlled Synthesis to Biomedical Applications, Macromolecular Bioscience, 2009, 9, 1154-1164 (Invited Feature Article)
16. Juan Wu, Xi-Qiu Liu, Yu-Cai Wang, Jun Wang*, Template-Free Synthesis of Biodegradable Nanogels with Tunable Sizes as Potential Carriers for Drug Delivery, Journal of Materials Chemistry, 2009, 19, 7856-7863
17. Feng Wang, Yu-Cai Wang, Li-Feng Yan, Jun Wang*, Biodegradable Vesicular Nanoparticles Based on Block Copolymer of Poly(e-Caprolactone) and Poly(Ethyl Ethylene Phosphate) for Drug Delivery, Polymer, 2009, 50, 5048-5054
18. Yu-Cai Wang, Hai Xia, Xian-Zhu Yang, Jun Wang*, Synthesis and Thermoresponsive Behaviors of Biodegradable Pluronic Analogs,Journal of Polymer Science Part A: Polymer Chemistry, 2009, 47, 6168-6179
19. You-Yong Yuan, Xi-Qiu Liu, Yu-Cai Wang, Jun Wang*, Gold Nanoparticles Stabilized by Thermosensitive Diblock Copolymers of Poly(ethylene glycol) and Polyphosphoester, Langmuir, 2009, 25, 10298-10304
20. Xian-Zhu Yang, Tian-Meng Sun, Shuang Dou, Juan Wu, Yu-Cai Wang, Jun Wang*, Block Copolymer of Polyphosphoester and Poly(L-Lactic Acid) Modified Surface for Enhancing Osteoblast Adhesion, Proliferation, and Function, Biomacromolecules, 2009, 10, 2213–2220
21. Ling-Yan Tang, Yu-Cai Wang,* Yang Li, Jin-Zhi Du, Jun Wang* , Shell-detachable micelles based on disulfide-linked block copolymer as potential carrier for intracellular drug delivery, Bioconjugate Chemistry, 2009, 20, 1095-1099 (most-accessed article during April-June 2009)
22. Yu-Cai Wang, Yang Li, Xian-Zhu Yang, You-Yong Yuan, Li-Feng Yan, Jun Wang*, Tunable Thermosensitivity of Biodegradable Polymer Micelles of Poly(ε-caprolactone) and Polyphosphoester Block Copolymers, Macromolecules, 2009, 42, 3026-3032
23. Meng-Hua Xiong, Juan Wu, Yu-Cai Wang, Lai-Sheng Li, Xiao-Bing Liu, Guang-Zhao Zhang, Li-Feng Yan, Jun Wang*, Synthesis of PEG-Armed and Polyphosphoester Core-Cross-Linked Nanogel by One-Step Ring-Opening Polymerization, Macromolecules, 2009, 42, 893-896
24. Yu-Cai Wang, Ling-Yan Tang, Jun Wang*, Thermoresponsive Block Copolymers of Poly(ethylene glycol) and Polyphosphoester: Thermo-Induced Self-Assembly, Biocompatibility and Hydrolytic Degradation, Biomacromolecules, 2009, 10, 66-73
25. You-Yong Yuan, Yu-Cai Wang, Jin-Zhi Du, Jun Wang* , Synthesis of Amphiphilic ABC 3-Miktoarm Star Terpolymer by Combination of Ring Opening Polymerization and “Click” Chemistry, Macromolecules, 2008, 41, 8620-8625
26. Jing Cheng, Jian-Xun Ding, Yu-Cai Wang, Jun Wang*, Synthesis and Characterization of Star-Shaped Block Copolymer of Poly(e-caprolactone) and Poly(ethyl ethylene phosphate) as Drug Carrier, Polymer, 2008, 49, 4784-4790
27. Xian-Zhu Yang, Yu-Cai Wang, Ling-Yan Tang, Hai Xia, Jun Wang* , Synthesis and Characterization of Amphiphilic Block Copolymer of Polyphosphoester and Poly(L-lactic acid), Journal of Polymer Science Part A: Polymer Chemistry, 2008, 46, 6425-6434
28. Yu-Cai Wang, Xi-Qiu Liu, Tian-Meng Sun, Meng-Hua Xiong, Jun Wang* , Functionalized Micelles from Polyphosphoester and Poly(e-caprolactone) Block Copolymer for Receptor-Mediated Drug Delivery, Journal of Controlled Release, 2008, 128, 32-40 (Most accessed paper)
29. Yu-Cai Wang, Ling-Yan Tang, Tian-Meng Sun, Chang-Hua Li, Meng-Hua Xiong, Jun Wang*, Self-assembled Micelles of Biodegradable Triblock Copolymers Based on Poly(ethyl ethylene phosphate) and Poly(epsilon-caprolactone) as Drug Carriers, Biomacromolecules, 2008, 9, 388-395
30. Yu-Cai Wang, Sheng-Yi Shen, Quan-Ping Wu, Dong-Ping Chen, Jun Wang*, Gustav Steinhoff, Nan Ma, Block Copolymerization of ε-Caprolactone and 2-Methoxyethyl Ethylene Phosphate Initiated by Aluminum Isopropoxide: Synthesis, Characterization, and Kinetics, Macromolecules, 2006, 39, 8992-8998
31. Chun-Sheng Xiao, Yu-Cai Wang, Jin-Zhi Du, Xue-Si Chen, Jun Wang*, Kinetics and Mechanism of 2-Ethoxy-2-oxo-1,3,2-dioxaphospholane Polymerization Initiated by Stannous Octoate, Macromolecules, 2006, 39, 6825-6831
32. Jin-Zhi Du, Dong-Ping Chen, Yu-Cai Wang, Chun-Sheng Xiao, Yi-Jie Lu, Jun Wang*, Guang-Zhao Zhang, Synthesis and Micellization of Amphiphilic Brush-Coil Block Copolymer Based on Poly(ε-caprolactone) and PEGylated Polyphosphoester,Biomacromolecules, 2006, 7, 1898-1903
33. 王均、杨显珠、王育才、唐凌燕,一种聚磷酸酯-聚乳酸三嵌段共聚物及其应用,中国发明专利,授权号:ZL 2008 1 0211948.6
34. 王均、王育才,一种聚磷酸酯-聚己内酯三嵌段共聚物及其应用,中国发明专利,授权号:ZL 2007 1 0198478.X