2002-2006,合肥工业大学化学院高分子材料与工程系,高分子化学学士
2006-2011,合肥微尺度物质科学国家实验室(筹),高分子科学博士
博士学位论文:小干扰RNA的纳米药物输送系统及其用于癌症治疗的研究
毕业后去向:中国科学技术大学生命科学学院,博士后
现联系方式:yangxz@mail.ustc.edu.cn
所获奖励:中国科学技术大学光华奖学金(2009年)
研究生期间发表论著:
1. Shuang Dou, Yan-Dan Yao, Xian-Zhu Yang, Tian-Meng Sun, Cheng-Qiong Mao, Er-Wei Song*, Jun Wang*, Anti-Her2 Single-Chain Antibody Mediated DNMTs-siRNA Delivery for Targeted Breast Cancer Therapy, Journal of Controlled Release, 2012, 161, 875-883
2. Xian-Zhu Yang, Shuang Dou, Yu-Cai Wang, Hong-Yan Long, Meng-Hua Xiong, Cheng-Qiong Mao, Yan-Dan Yao, Jun Wang*, Single-Step Assembly of Cationic Lipid-Polymer Hybrid Nanoparticles for Systemic Delivery of siRNA, ACS Nano, 2012, 6, 4955-4965
3. Meng-Hua Xiong, Yan Bao, Xian-Zhu Yang, Yu-Cai Wang, Baolin Sun*, Jun Wang*, Lipase-Sensitive Polymeric Triple-Layered Nanogel for “On-Demand” Drug Delivery, Journal of the American Chemical Society, 2012, 134, 4355-4362
4. Xian-Zhu Yang, Jin-Zhi Du, Cheng-Qiong Mao, Hong-Yan Long, Jun Wang*, Sheddable Ternary Nanoparticles for Tumor Acidity-Targeted siRNA Delivery , ACS Nano, 2012, 6, 771-781 (most read articles, ACS Nano, Jan., 2012)
5. Xian-Zhu Yang, Shuang Dou, Tian-Meng Sun, Cheng-Qiong Mao, Hong-Xia Wang, Jun Wang*, Systemic delivery of siRNA with cationic lipid assisted PEG-PLA nanoparticles for cancer therapy, Journal of Controlled Release, 2011, 156(2), 203-211 (Top 25 Hottest Articles, Journal of Controlled Release, October to December 2011)
6. Xi-Qiu Liu, Jin-Zhi Du, Chu-Pei Zhang, Fang Zhao, Xian-Zhu Yang, Jun Wang*, Brush-shaped polycation with poly(ethylenimine)-b-poly(ethylene glycol) side chains as highly efficient gene delivery vector, International Journal of Pharmaceutics, 2010, 392, 118-126
7. Yu-Cai Wang, You-Yong Yuan , Jin-Zhi Du, Xian-Zhu Yang, Jun Wang* , Recent Progress in Polyphosphoesters: From Controlled Synthesis to Biomedical Applications, Macromolecular Bioscience, 2009, 9, 1154-1164 (Invited Feature Article)
8. Yu-Cai Wang, Hai Xia, Xian-Zhu Yang, Jun Wang*, Synthesis and Thermoresponsive Behaviors of Biodegradable Pluronic Analogs, Journal of Polymer Science Part A: Polymer Chemistry, 2009, 47, 6168-6179
9. Xian-Zhu Yang, Tian-Meng Sun, Shuang Dou, Juan Wu, Yu-Cai Wang, Jun Wang*, Block Copolymer of Polyphosphoester and Poly(L-Lactic Acid) Modified Surface for Enhancing Osteoblast Adhesion, Proliferation, and Function, Biomacromolecules, 2009, 10, 2213–2220
10. Yu-Cai Wang, Yang Li, Xian-Zhu Yang, You-Yong Yuan, Li-Feng Yan, Jun Wang*, Tunable Thermosensitivity of Biodegradable Polymer Micelles of Poly(ε-caprolactone) and Polyphosphoester Block Copolymers, Macromolecules, 2009, 42, 3026-3032
11. Xian-Zhu Yang, Yu-Cai Wang, Ling-Yan Tang, Hai Xia, Jun Wang* , Synthesis and Characterization of Amphiphilic Block Copolymer of Polyphosphoester and Poly(L-lactic acid), Journal of Polymer Science Part A: Polymer Chemistry, 2008, 46, 6425-6434
12. 王均、杨显珠、王育才、唐凌燕,一种聚磷酸酯-聚乳酸三嵌段共聚物及其应用,中国发明专利,授权号:ZL 2008 1 0211948.6