中国科学技术大学 华南理工大学中文|English
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2002-2006,中国科学技术大学生命科学学院,生命科学学士

2006-2011,合肥微尺度物质科学国家实验室(筹),生物材料博士

博士学位论文:纳米药物载体输送小干扰RNA和化疗药物用于乳腺癌治疗的研究

毕业后去向:美国佐治亚理工学院,博士后

现联系方式:suntim@mail.ustc.edu.cn

所获奖励:中国科学技术大学优秀毕业生(2011年)、通用电器基金会科技创新一等奖(2011年)、中国科学院“院长奖”(2011年)、中国科学院朱李月华优秀博士生奖(2010年)、中国科学技术大学光华奖学金(2008年)、研究生创新基金(2008年)

研究生期间发表论著:

1. Yang Li, Feng Wang, Tian-Meng Sun, Jin-Zhi Du, Xian-Zhu Yang*, Jun Wang*, Intracellular Responsive Polymer Nanoparticles Modulated by the Surface for Enhanced Drug Delivery, Science China Chemistry, accepted

2. Weiwei Liu, Yucai Wang, Yang Li, Feng Wang, Xianzhu Yang,* Tianmeng Sun, Jinzhi Du, Jun Wang*, Multiresponsive Polymer Assemblies Achieved by A Subtle Chain Terminal Modification, Chinese Journal of Chemistry, 2013, online

3. Tian-Meng Sun, Yu-Cai Wang, Feng Wang, Jin-Zhi Du, Cheng-Qiong Mao, Chun-Yang Sun, Rui-Zhi Tang, Yang Liu, Jing Zhu, Yan-Hua Zhu, Xian-Zhu Yang, Jun Wang*, Cancer stem cell therapy using doxorubicin conjugated to gold nanoparticles via hydrazone bonds, Biomaterials, 2014, 35, 836-845

4. Juan Wu, Tian-Meng Sun (co-first author), Xian-Zhu Yang*, Jing Zhu, Xiao-Jiao Du, Yan-Dan Yao, Meng-Hua Xiong, Hong-Xia Wang, Yu-Cai Wang, Jun Wang*, Enhanced Drug Delivery to Hepatocellular Carcinoma with a Galactosylated Core-Shell Polyphosphoester Nanogel, Biomaterial Sciences, 2013, 1, 1143-1150 (Top 10 Most-accessed Biomaterials Science articles-Q3 2013)

5. Shuang Dou, Yan-Dan Yao, Xian-Zhu Yang, Tian-Meng Sun, Cheng-Qiong Mao, Er-Wei Song*, Jun Wang*, Anti-Her2 Single-Chain Antibody Mediated DNMTs-siRNA Delivery for Targeted Breast Cancer Therapy, Journal of Controlled Release, 2012, 161, 875-883

6. Yan-Dan Yao, Tian-Meng Sun (co-first author), Song-Yin Huang, Shuang Dou, Ling Lin, Jia-Ning Chen, Jian-Bin Ruan, Cheng-Qiong Mao, Feng-Yan Yu, Mu-Sheng Zeng, Jian-Ye Zang, Qiang Liu, Feng-Xi Su, Peter Zhang, Judy Lieberman*, Jun Wang*, Erwei Song*, Targeted Delivery of PLK1-siRNA by ScFv Suppresses Her2+ Breast Cancer Growth and Metastasis, Science Translational Medicine, 2012, 4, 130ra48 (Highlighted by Nature Review Cancer)

7. Yu-Cai Wang, Feng Wang, Tian-Meng Sun, Jun Wang*, Redox-Responsive Nanoparticles from the Single Disulfide Bond-Bridged Block Copolymer as Drug Carriers for Overcoming Multi-Drug Resistance in Cancer Cells, Bioconjugate Chemistry, 2011, 22, 1939-1945

8. Xian-Zhu Yang, Shuang Dou, Tian-Meng Sun, Cheng-Qiong Mao, Hong-Xia Wang, Jun Wang*, Systemic delivery of siRNA with cationic lipid assisted PEG-PLA nanoparticles for cancer therapy, Journal of Controlled Release, 2011, 156(2), 203-211 (Top 25 Hottest Articles, Journal of Controlled Release, October to December 2011)

9. Feng Wang, Yu-Cai Wang, Shuang Dou, Meng-Hua Xiong, Tian-Meng Sun, Jun Wang*, Doxorubicin-Tethered Responsive Gold Nanoparticles Facilitate Intracellular Drug Delivery for Overcoming Multidrug Resistance in Cancer Cells, ACS Nano, 2011, 5, 3679-3692 (most read article, Q2, 2011)

10. Cheng-Qiong Mao, Jin-Zhi Du, Tian-Meng Sun, Yan-Dan Yao, Pei-Zhuo Zhang, Er-Wei Song, Jun Wang*, A BiodegradableAmphiphilic and Cationic Triblock Copolymer for the Delivery of siRNA Targeting the Acid Ceramidase Gene for Cancer Therapy, Biomaterials, 2011, 32, 3124-3133

11. Tian-Meng Sun, Jin-Zhi Du, Yan-Dan Yao, Cheng-Qiong Mao, Shuang Dou, Song-Yin Huang, Pei-Zhuo Zhang, Kam W. Leong, Er-Wei Song*, Jun Wang*, Simultaneous Delivery of siRNA and Paclitaxel via a “Two-in-One” Micelleplex Promotes Synergistic Tumor Suppression, ACS Nano, 2011, 5, 1483-1494

12. Xi-Qiu Liu, Wen-Jing Song, Tian-Meng Sun, Pei-zhuo Zhang, Jun Wang*, Targeted delivery of antisense inhibitor of miRNA for antiangiogenesis therapy using cRGD-functionalized nanoparticles, Molecular Pharmaceutics, 2011, 8, 250-259 (Most read articles, Jan. and March, April 2011)

13. Jin-Zhi Du, Tian-Meng Sun (co-first author), Wen-Jing Song, Juan Wu, Jun Wang*, A Tumor-Acidity-Activated Charge-Conversional Nanogel as an Intelligent Vehicle for Promoted Tumoral-Cell Uptake and Drug Delivery, Angewandte Chemie-International Edition, 2010, 49, 3621-3626

14. Yu-Cai Wang, Yang Li, Tian-Meng Sun, Meng-Hua Xiong, Juan Wu, Yi-Yan Yang, Jun Wang* , Core-Shell-Corona Micelle Stabilized by Reversible Cross-Linkage for Intracellular Drug Delivery , Macromolecular Rapid Communications, 2010, 31, 1201-1206

15. Wen-Jing Song, Jin-Zhi Du, Tian-Meng Sun, Pei-Zhuo Zhang, Jun Wang*, Gold Nanoparticles Capped with Polyethylenimine for Enhanced siRNA Delivery, Small, 2010, 6, 239-246

16. Xian-Zhu Yang, Tian-Meng Sun, Shuang Dou, Juan Wu, Yu-Cai Wang, Jun Wang*, Block Copolymer of Polyphosphoester and Poly(L-Lactic Acid) Modified Surface for Enhancing Osteoblast Adhesion, Proliferation, and Function, Biomacromolecules, 2009, 10, 2213–2220

17. Tian-Meng Sun, Jin-Zhi Du, Li-Feng Yan, Hai-Quan Mao, Jun Wang *, Self-Assembled Biodegradable Micellar Nanoparticles of Amphiphilic and Cationic Block Copolymer for siRNA Delivery, Biomaterials, 2008, 29, 4348-4355

18. Yu-Cai Wang, Xi-Qiu Liu, Tian-Meng Sun, Meng-Hua Xiong, Jun Wang* , Functionalized Micelles from Polyphosphoester and Poly(e-caprolactone) Block Copolymer for Receptor-Mediated Drug Delivery, Journal of Controlled Release, 2008, 128, 32-40 (Most accessed paper)

19. Zhen-Zhen Lu, Juan Wu, Tian-Meng Sun, Jing Ji, Li-Feng Yan, Jun Wang*, Biodegradable Polycation and Plasmid DNA Multilayer Film for Prolonged Gene Delivery to Mouse Osteoblasts, Biomaterials, 2008, 29, 733-741

20. Yu-Cai Wang, Ling-Yan Tang, Tian-Meng Sun, Chang-Hua Li, Meng-Hua Xiong, Jun Wang*, Self-assembled Micelles of Biodegradable Triblock Copolymers Based on Poly(ethyl ethylene phosphate) and Poly(epsilon-caprolactone) as Drug Carriers, Biomacromolecules, 2008, 9, 388-395

21. Jin-Zhi Du, Tian-Meng Sun, Song-Qing Weng, Xue-Si Chen, Jun Wang*, Synthesis and Characterization of Photocrosslinked Hydrogel Based on Biodegradable Polyphosphoester and Poly(ethylene glycol) Copolymer, Biomacromolecules, 2007, 8, 3375-3381

22. 王均、孙天盟、杜金志,一种药物载体及其应用,中国发明专利,申请号:200810246720.0

23. 王均、杜金志、孙天盟,一种聚乙二醇单甲醚-聚己内酯-聚磷酸酯三嵌段共聚物及其制备的siRNA药物载体,中国发明专利,授权号:ZL 2008 1 0055945.8

24. 宋尔卫、姚燕丹、王均、孙天盟、张佩琢,一种用于治疗乳腺癌的融合蛋白及其应用,中国发明专利,申请号:200910040537.X,申请日期,2009年6月25日


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