中国科学技术大学 华南理工大学中文|English
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2004-2008,中国科技大学生命科学学院,生物科学理学学士

2008-2013,中国科技大学高分子科学与工程系,生物材料理学博士

博士学位论文:基于纳米胶束的Micelleplex输送小干扰RNA用于癌症治疗

毕业后去向:Postdoc of UT Southwestern Medical Center

现联系方式: maocq@mail.ustc.edu.cn

所获奖励:2012年中国科学技术大学“求是”奖学金;2012年中国科学技术大学“光华”奖学金;2012年“研究生国家奖学金”;2012年“通用电气基金会科技创新奖”三等奖;2013年中国科学技术大学“优秀博士毕业生”

研究生期间发表论著:

1. Cheng-Qiong Mao, Meng-Hua Xiong, Yang Liu, Song Shen, Xiao-Jiao Du, Xian-Zhu Yang, Pei-Zhuo Zhang, Shuang Dou, Jun Wang*, Synthetic Lethal Therapy for KRAS Mutant Non-Small-Cell Lung Carcinoma with Nanoparticle-Mediated CDK4 siRNA Delivery, Molecular Therapy (accepted).

2. Jin-Zhi Du, Cheng-Qiong Mao (co-first author), You-Yong Yuan, Xian-Zhu Yang, Jun Wang*, Tumor Extracellular Acidity-Activated Nanoparticles as Drug Delivery Systems for Enhanced Cancer Therapy, Biotechnology Advances, 2013, Doi: 10.1016/j.biotechadv.2013.08.002 (invited review)

3. You-Yong Yuan, Chen-Qiong Mao (co-first author), Xiao-Jiao Du, Jin-Zhi Du, Feng Wang, Jun Wang*, Surface Charge Switchable Nanoparticles based on Zwitterionic Polymer for Enhanced Drug Delivery to Tumor, Advanced Materials, 2012, 24, 5476-5480

4. Cheng-Qiong Mao, Jin-Zhi Du, Tian-Meng Sun, Yan-Dan Yao, Pei-Zhuo Zhang, Er-Wei Song, Jun Wang*, A Biodegradable Amphiphilic and Cationic Triblock Copolymer for the Delivery of siRNA Targeting the Acid Ceramidase Gene for Cancer Therapy, Biomaterials. 2011, 32, 3124-3133

5. Tian-Meng Sun, Yu-Cai Wang, Feng Wang, Jin-Zhi Du, Cheng-Qiong Mao, Chun-Yang Sun, Rui-Zhi Tang, Yang Liu, Jing Zhu, Yan-Hua Zhu, Xian-Zhu Yang, Jun Wang*, Cancer Stem Cell Therapy Using Doxorubicin Conjugated Gold Nanoparticles via Hydrazone Bonds, Biomaterials, 2014, 35, 836-845

6. Tao Xing, Chengqiong Mao, Bin Lai, Lifeng Yan*, Synthesis of Disulfide-cross-linked Polypeptide Nanogel Conjugated with a Near Infrared Fluorescence Probe for Direct Imaging of Reduction Induced Drug Release, ACS Applied Materials & Interfaces, 2012, 4, 5622-5672

7. Shuang Dou, Yan-Dan Yao, Xian-Zhu Yang, Tian-Meng Sun, Cheng-Qiong Mao, Er-Wei Song*, Jun Wang*, Anti-Her2 Single-Chain Antibody Mediated DNMTs-siRNA Delivery for Targeted Breast Cancer Therapy, Journal of Controlled Release, 2012, 161, 875-883

8. Yuanzeng Min, Cheng-Qiong Mao, Siming Chen, Guolin Ma, Jun Wang*, Yangzhong Liu*, Combating the Drug Resistance of Cisplatin Using a Platinum Prodrug Based Delivery System, Angewandte Chemie-International Edition, 2012, 51, 6742-6747

9. Xian-Zhu Yang, Shuang Dou, Yu-Cai Wang, Hong-Yan Long, Meng-Hua Xiong, Cheng-Qiong Mao, Yan-Dan Yao, Jun Wang*, Single-Step Assembly of Cationic Lipid-Polymer Hybrid Nanoparticles for Systemic Delivery of siRNA, ACS Nano, 2012, 6:, 955-4965

10. Yan-Dan Yao, Tian-Meng Sun, Song-Yin Huang, Shuang Dou, Ling Lin, Jia-Ning Chen, Jian-Bin Ruan, Cheng-Qiong Mao, Feng-Yan Yu, Mu-Sheng Zeng, Jian-Ye Zang, Qiang Liu, Feng-Xi Su, Peter Zhang, Judy Lieberman*, Jun Wang*, Erwei Song*, Targeted Delivery of PLK1-siRNA by ScFv Suppresses Her2+ Breast Cancer Growth and Metastasis, Science Translational Medicine, 2012, 4, 130ra48

11. Xian-Zhu Yang, Jin-Zhi Du, Cheng-Qiong Mao, Hong-Yan Long, Jun Wang*, Sheddable Ternary Nanoparticles for Tumor Acidity-Targeted siRNA Delivery, ACS Nano, 2012, 6, 71-781

12. Jin-Zhi Du, Xiao-Jiao Du, Cheng-Qiong Mao, Jun Wang*, Tailor-Made Dual pH-Sensitive Polymer-Doxorubicin Nanoparticles for Efficient Anticancer Drug Delivery, Journal of the American Chemical Society, 2011, 133, 17560-17563

13. Xian-Zhu Yang, Shuang Dou, Tian-Meng Sun, Cheng-Qiong Mao, Hong-Xia Wang, Jun Wang*, Systemic delivery of siRNA with cationic lipid assisted PEG-PLA nanoparticles for cancer therapy. Journal of Controlled Release. 2011, 156, 203-211

14. Tian-Meng Sun, Jin-Zhi Du, Yan-Dan Yao, Cheng-Qiong Mao, Shuang Dou, Song-Yin Huang, Pei-Zhuo Zhang, Kam W. Leong, Er-Wei Song*, Jun Wang*, Simultaneous Delivery of siRNA and Paclitaxel via a “Two-in-One” Micelleplex Promotes Synergistic Tumor Suppression, ACS Nano, 2011, 5, 1483-1494

15. Yuanzeng Ming, Chengqiong Mao, Decheng Xu, Jun Wang, Yangzhong Liu*, Gold Nanorods for Platinum Based Prodrug Delivery, Chemical Communications, 2010, 46, 8424-8426

16. Song Shen,Cheng-Qiong Mao,Xian-Zhu Yang*, Xiao-Jiao Du,Yang Liu, Yan-Hua Zhu, Jun Wang*
Cationic Lipid-Assisted Polymeric NanoparticlesMediated GATA2 siRNA Delivery for Synthetic Lethal Therapy of KRAS Mutant Non-Small-Cell Lung Carcinoma, Molecular Pharmaceutics, online

17.王均、毛成琼、杜金志、张佩琢,聚乙二醇单甲醚-聚己内酯-聚磷酸酯共聚物及其应用,中国发明专利,申请号:201110449824.3

18.王均、刘熙秋、熊梦华、毛成琼、王红霞,嵌段共聚物与液体组合物和核酸制剂及其制备方法和应用,中国发明专利,申请号:201110329184.2

19.王均、杜金志、孙春阳、都小姣、毛成琼,一种聚乙二醇单甲醚-聚磷酸酯两嵌段共聚物及其阿霉素键合药,中国发明专利,申请号:201110317008.7


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